Endocrine Abstracts

Patients with Grave’s disease (GD) are more prone to develop low serum calcium values than patients operated on because of goitre after total thyroidectomy. Moreover, some patients with GD achieve hypercalcemia probably due to active bone disease. We have used citrate-calcium clamping (CiCa) in order to investigate the calcium homeostasis in detail in patients with Grave’s disease.Material and method: Our series of patients undergoing total thy...

Background: Pheochromocytomas are rare tumours arising from adrenal medulla. Recent findings show that about 30–40% of pheochromocytomas are caused by germline mutations in one of the ten hereto known susceptibility genes: SDHA, SDHB, SDHC, SDHD, SDHAF2, RET, VHL, NF1, TMEM127 and MAX. This list of genes is constantly growing. These ten genes together consist of 128 exons and a genetic screening test is both extensive time-consuming and expensive. We introduce utilizing N...